Figure 6. Schematic diagrams of light-mediated chemical reactions in radiation-sensitive lipids.
- Photo-oxidation of lipids containing vinyl ether linkages by reactive oxygen species (generated by a series of photo sensitizers).
- Photo isomerization of azobenzene groups undergo wavelength-specific manner radiation leading to cis-trans (420/360nm) conformational changes.
- i, ii and iii: Photo cleavable lipids that after light radiation their breakdown products destabilize liposome membrane
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i: Photo-polymerizable phospholipid (DC8,9PC) graphic illustration.ii: Description of DC8,9PC chemical modifications and cross linking upon UV treatment