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. Author manuscript; available in PMC: 2011 Dec 22.
Published in final edited form as: Biochemistry. 2009 Mar 3;48(8):1754–1762. doi: 10.1021/bi801291q

Figure 5. NSC 622124 Inhibits HsEg5 and KLP61F Binding to MTs.

Figure 5

Co-sedimentation assays containing HsEg5, MTs, MgAMPPNP and either DMSO or 25 µM NSC 622124 were performed as described in the Methods, and supernatant (S) and pellet (P) fractions were subjected to SDS-PAGE. The positions of molecular weight markers, tubulin (T), and relevant motor (M) are indicated.