Table 2.
Comparison of different minimotif filters
| Minimotif filter | Area under ROC curve | P-value | Discrimination ratio | Reference |
|---|---|---|---|---|
| Frequency score | 0.7 | 0.08 | ND | (11,13) |
| Cellular function | 0.7 | 0.12 | 4.6 | (13) |
| Cellular function + frequency score | 0.9 | 0.0002 | – | (13) |
| Molecular function | 0.8 | 0.03 | 2.9 | (13) |
| Molecular function + frequency score | 0.9 | 0.002 | – | (13) |
| Protein–protein interaction | 0.9 | 0.001 | 12.5 | (11) |
| Genetic interaction | – | – | 7.3 | Submitted for publication |
| Surface prediction filter | 0.3 | 1 | – | (7) |
| Multifilter | 0.94 | 9.7 e−278 | – | Submitted for publication |