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. 2011 Dec 1;40(Database issue):D972–D977. doi: 10.1093/nar/gkr1183

Table 1.

Common mutated genes in copy number alteration regions of NSCLC

Non-small cell lung carcinoma Alteration Genes with at least five somatic mutations
AD Mutated genes in amplified regions (30 genes) APC, BRAF, CDC42BPA, CDKN2A, CTNNB1, EGFR, EPHA3, EPHA5, EPHA7, EPHB6, FGFR4, FLT1, INSRR, JAK2, KDR, KIAA1804, KRAS, LMTK2, MET, NRAS, NTRK1, PAK7, PDGFRA, PIK3C3, PIK3CA, PIK3CG, PRKDC, RB1, ROBO2, TERT
Mutated genes in deleted regions NOTCH1, PTEN, TP53
SCC Mutated genes in amplified regions BRAF, CDKN2A, EGFR, KRAS, PIK3CA
Mutated genes in deleted regions TP53