Table 5. Median adverse event rate by CHMP criteria.

Adverse event	IC patients (%)	VICT controls (%)	PNV controls (%)
Local
Ecchymosis	3.1 (2.0 to 4.2; n = 2)	0.0 (0.0 to 0.0; n = 1)	–
Induration	18.9 (10.2 to 30.0; n = 5)	11.0 (6.3 to 15.0; n = 3)	–
System ic
Fever	7.1 (0.0 to 23.3; n = 14)	5.0 (0.0 to 16.7; n = 5)	10.2 (10.0 to 10.3; n = 2)
Malaise	23.6 (0.8 to 44.0; n = 8)	12.0 (0.0 to 25.9; n = 5)	22.1 (20.0 to 24.1; n = 2)
Shivering	10.2 (10.2 to 10.2; n = 1)	16.3 (16.3 to 16.3; n = 1)	–

Values in parentheses show the reported range of adverse events and number of studies; IC = immunocompromised; VICT = vaccinated immunocompetent; PNV = placebo or no vaccination.