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. 2011 Dec 22;6(12):e29322. doi: 10.1371/journal.pone.0029322

Table 1. Main characteristics of the 80 HIV-infected MSM at acute HCV infection diagnosis reported by physicians, medical questionnaire, HEPAIG study, 2006–2007.

Region of care Paris area 48 (60.0)
Age, years 40 (36–44)
Year of HCV diagnosis 2006 41 (51)
2007 39 (49)
Year of HIV diagnosis <1996 30 (37.5)
1996–1999 14 (17.5)
≥2000 36 (45.0)
Time between HIV and HCV diagnosis, years 9 (3–13.5)
HIV clinical stage primary infection 2 (2.5)
asymptomatic 58 (72.5)
symptomatic 12 (15.0)
AIDS-defining illness 8 (10.0)
HIV viral load undetectablea under HAART 46 (57.5)
detectable without HAART 22 (26.2)
detectable under HAART 10 (12.5)
missing 2 (2.5)
CD4 cell count/mm3 >500 46 (57.5)
350–500 20 (25.0)
200–349 11 (13.7)
<200 3 (3.8)
Circumstances of HCV diagnosisb systematic anti-HCV screening 17 (21.2)
increased ALT level 62 (77.5)
at risk behaviour 27 (33.7)
jaundice 9 (11.2)
Concomitant diagnosis of STI yes 29 (36.2)
no 43 (53.8)
missing 8 (10.0)
Acute HCV infection confirmedc 59 (74.0)
possibled 16 (20.0)
re-infectione 5 (6.0)
ALT level, xULN ≤1 6 (7.5)
>1–<3 10 (12.5)
3–5 14 (17.5)
>5–7 8 (10.0)
>7–10 4 (5.0)
>10 35 (43.7)
not available 3 (3.7)
HCV viral load,log10, IU/mL 5.9(5.1–6.5)
HCV genotype 1 26 (32.5)
3 8 (10.0)
4 44 (55.0)
not available 2 (2.5)

Note. Data are no. (%) of patients or median values (inter-quartile range); MSM, men who have sex with men; HAART, highly active antiretroviral treatment; STI, sexually transmitted infection; ALT, alanine aminotransferase; ULN, upper limit of normal; a<50 copies/mL; bseveral possible answers; canti-HCV (+) within one year after anti-HCV (-) or HCV RNA (+) within one year after both documented anti-HCV (-) and HCV RNA (-); dHCV RNA (+) either: i) within one year after two documented HCV RNA (-), or, ii) with symptoms of acute hepatitis and ALT level >10xULN within one year after regular controls of normal ALT (other causes excluded); epossible acute HCV infection following primary infection with confirmed viral clearance.