Figure 1. Proteome comparison reveals 30 proteins conserved in primate malaria parasites but absent in rodent malaria parasites.

Genes were considered specific to a group of parasites if conserved in all in-group species (global protein sequence PID> = 40) but not in any of the out-group species (PID< = 15). In particular, primate-parasite specific genes are genes conserved in the three primate parasite proteomes but not in any of the three rodent parasite proteomes. The Venn diagram shows numbers of species subset-specific genes identified for all possible species combinations. Putative primate parasite-specific genes (30) are shown in bold. Note that gene numbers do not add up to species totals because genes with PIDs between 15% and 40% are not included.