Table 4. Effect of GATA6 knockdown on reprogramming.
| Experimental Reprogramming Recipes (Over- expression & GATA6 Knockdown) | Predicted iPSC ReprogrammingEfficiency | Expression similarity to the ESC state | ||
| RMSD | Pearson (r) | Spearman (r) | ||
| OCT4_SOX2_MYC_PRDM14&GATA6 | 0.613516 | 0.081913 | 0.961799 | 0.965876 |
| OCT4_SOX2_KLF4_PRDM14&GATA6 | 0.616624 | 0.044800 | 0.989263 | 0.987023 |
| OCT4_SOX2_KLF4_MYC_PRDM14&GATA6 | 0.586480 | 0.079915 | 0.964070 | 0.968269 |
| OCT4_SOX2_KLF4_MYC&GATA6 | 0.627800 | 0.079739 | 0.964028 | 0.966130 |
| OCT4_SOX2_KLF4&GATA6 | 0.570686 | 0.044417 | 0.990064 | 0.987042 |
| OCT4_MYC_KLF4&GATA6 | 0 | 0.113600 | 0.895640 | 0.923445 |
| SOX2_MYC_KLF4&GATA6 | 0 | 0.122500 | 0.881400 | 0.933425 |
| OCT4_MYC_PRDM14&GATA6 | 0 | 0.314400 | −0.003200 | −0.100370 |
| SOX2_MYC_PRDM14&GATA6 | 0 | 0.387400 | −0.328900 | −0.342112 |