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. 2011 Dec 22;7(12):e1002300. doi: 10.1371/journal.pcbi.1002300

Table 4. Effect of GATA6 knockdown on reprogramming.

Experimental Reprogramming Recipes (Over- expression & GATA6 Knockdown) Predicted iPSC ReprogrammingEfficiency Expression similarity to the ESC state
RMSD Pearson (r) Spearman (r)
OCT4_SOX2_MYC_PRDM14&GATA6 0.613516 0.081913 0.961799 0.965876
OCT4_SOX2_KLF4_PRDM14&GATA6 0.616624 0.044800 0.989263 0.987023
OCT4_SOX2_KLF4_MYC_PRDM14&GATA6 0.586480 0.079915 0.964070 0.968269
OCT4_SOX2_KLF4_MYC&GATA6 0.627800 0.079739 0.964028 0.966130
OCT4_SOX2_KLF4&GATA6 0.570686 0.044417 0.990064 0.987042
OCT4_MYC_KLF4&GATA6 0 0.113600 0.895640 0.923445
SOX2_MYC_KLF4&GATA6 0 0.122500 0.881400 0.933425
OCT4_MYC_PRDM14&GATA6 0 0.314400 −0.003200 −0.100370
SOX2_MYC_PRDM14&GATA6 0 0.387400 −0.328900 −0.342112