Table 2.

Laboratory value differences among patients above and below SF 1.5ULN

Variable*	SF≤1.5ULN (N=500)	SF>1.5ULN (N=128)	P value†
AST (U/L)	43 (31–62)	58 (35–85)	<0.0001
ALT (U/L)	58 (38–85)	81 (53–132)	<0.0001
Gamma glutamyl transferase (U/L)	43 (28–77)	59 (37–114)	0.0001
Direct bilirubin (mg/dL)	0.10 (0.10–0.20)	0.10 (0.10–0.20)	0.02
Platelets (K/cmm)	246 (203–287)	230 (195–273)	0.015
Hemoglobin (g/dL)	14.3 (13.4–15.2)	15.0 (13.8–15.7)	0.0001
Serum iron (μg/dL)	84 (65–106)	106 (80–128)	<0.0001
Total iron binding capacity (μg/dL)	371 (331–417)	345 (301–388)	<0.0001
Transferrin saturation (iron/TIBC)	0.22 (0.17–0.29)	0.29 (0.23–0.41)	<0.0001
Serum ferritin (ng/mL)	121 (71–216)	547 (417–777)	<0.0001

^*Values are medians (IQR)

^†P values from Wilcoxon rank sum test.