Table 2.
Organizational Considerations for Review
| Cell Sources | Primary hepatocytes | human adult livers (liver not transplantable, liver resections) human fetal livers healthy donor animals |
| Cell lines | tumor derived (C3A, HepG2) immortalized normal hepatocytes |
|
| Progenitor cells | Induced pluripotent stem cell (iPS cells) embryonic stem cells fetal stem cells adult stem cells (oval, mesenchymal stem cells, other) |
|
| Hepatocyte-like | matured in vitro matured in vivo |
|
| Other | lymphocytes, etc. | |
|
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| Liver Abnormality | Acute liver failure Inherited metabolic liver disease Hepatitis (alcoholic, viral) Cirrhosis (cholestatic, other) Liver cancer (hepatocellular, cholangiocarcinoma) Recurrent disease after transplantation Rejection after transplantation |
|