Table 1.

Classification of adverse drug reactions [1,4,5]

Type A: Predictable

Type B: Unpredictable

• Drug overdose • Secondary drug effects • Side effects • Drug interactions

• Drug allergy: an immunologically mediated ADR • Pseudoallergic (non-allergic): a reaction with the same clinical manifestations as an allergic reaction, but that lacks immunological specificity • Drug intolerance: an undesirable pharmacologic effect that occurs at low and sometimes sub-therapeutic doses of the drug that are not caused by underlying abnormalities of metabolism or drug excretion • Drug idiosyncrasy: an abnormal/unexpected effect, usually caused by underlying abnormalities of metabolism, excretion, or bioavailability

ADR: adverse drug reaction