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Risk factors for the development of drug allergy [15]
| • Patient-related factors: • Age: young/middle-aged adults > infants/elderly • Gender: Women > men • Genetic polymorphisms • Viral infections: HIV, herpes viruses • Previous reaction to the drug |
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| • Drug-related factors: • High molecular weight compounds and hapten-forming drugs are more immunogenic • Route: topical > intravenous/intramuscular > oral • Dose: frequent/prolonged > single dose |
HIV: human immunodeficiency virus
