. Author manuscript; available in PMC: 2011 Dec 23.

Published in final edited form as: J Neurol Neurosurg Psychiatry. 2010 Sep 14;82(3):247–253. doi: 10.1136/jnnp.2010.211144

Table 3.

Multivariate logistic regression models of moderate/severe neurocognitive dysfunction after stepwise elimination for postoperative day 1

	OR (95% CI)	p Value
Model 1
Age	1.14 (1.06 to 1.25)	0.0003^*
Years of education	***	***
Previous carotid endarterectomy	***	***
Previous cerebrovascular accident	***	***
Ipsilateral stenosis	***	***
Diabetes mellitus	***	***
Surgery duration	***	***
Midazolam dose	***	0.08
Apolipoprotein E-ε4	***	***
Inducible nitric oxide synthase	***	***
C3F⁺	3.05 (1.03 to 9.73)	0.045^*
Y402H⁺⁺	6.41 (1.70 to 25.96)	0.006^*
Whole final model	***	0.0001^*
Model 2^†
Age	1.12 (1.04 to 1.22)	0.002^*
Midazolam dose	***	0.12
C3F⁺/Y402H⁺⁺	7.82 (1.09 to 72.0)	0.04^*
Whole final model	***	0.0001^*

All independent variables listed were included in the model before stepwise elimination. All p values were determined from likelihood ratio tests; the OR for age is presented as per year. C3F⁺ refers to subjects with at least one F allele. Y402H⁺⁺ refers to subjects with two copies of the Y402H allele. C3F⁺/Y402H⁺⁺ refers to subjects with at least one F allele and two copies of the Y402H allele.

Statistically significant

Statistically non-significant independent variables are denoted ***.

^†

For Model 2, only factors remaining after stepwise elimination are displayed.