Table 1.

Perception in Schizophrenia: Neuroimaging and Neurophysiological Tasks

Gain control: processes that allow sensory systems to adapt and optimize their response levels to take into account their immediate context, to make best use of a limited dynamic signaling range.

Tasks recommended for adaptation for use in clinical trial contexts

Steady-state visual evoked potentials to magnocellular- vs parvocellular-biased stimuli

Efference copy/corollary discharge: ERP paradigm

Prepulse inhibition of startle: fMRI paradigm

Already mature task

Mismatch negativity: ERP paradigm

Integration: the processes linking the output of neurons that code local attributes of a scene into global complex structure

Tasks recommended for adaptation for use in clinical trial contexts

Contour integration task: fMRI and ERP paradigms

Coherent motion detection task: fMRI paradigm

Note: ERP, event-related potential; fMRI, functional magnetic resonance imaging.