Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Decreased expression of CD8αβ is observed in activated CD8 T cells in E8I-deficient mice. Splenocytes from WT and E8I−/− mice infected 8, 15, and 45 days previously with LCMV-Armstrong were stained for CD8α, CD8β, and CD44. Bottom row shows data from LCMV immune animals 8 days after LCMV-cl.13 reinfection. The median fluorescent intensity of CD8α and CD8β is indicated in lower right quadrant of left panels. Arrows highlight CD44high CD8 T cells with reduced CD8α expression.
