Table 1.
Mean ± SD [95% CI] of all assessed parameters for controls and diabetics. The p-values are based on Wilcoxon tests to determine significant differences between the two groups.
| controls | diabetics | p-value | |
|---|---|---|---|
| age [years] | 57±4 [54 – 60] | 59±4 [57 – 62] | 0.264 |
| BMI [kg/m2] | 27.4±4.4 [24.8 – 30.1] | 26.8±3.2 [24.9 – 28.8] | 0.960 |
|
| |||
| glucose (fasting blood) [mg/dl] | 87±10 [81–93] | 166±87 [114 – 218] | <0.001 |
| HbA1c (fasting blood) [%] | 5.8±0.3 [5.6 – 5.9] | 7.6±1.7 [6.7 – 8.8] | <0.001 |
| vitamin D (fasting blood) [ng/ml] | 30±12 [23 – 38] | 29±13 [21 – 37] | 0.724 |
| calcium (fasting blood) [mg/dl] | 9.6±0.3 [9.4 – 9.7] | 9.5±0.3 [9.3 – 9.7] | 0.840 |
| PTH (fasting blood) [pg/ml] | 36±15 [26 – 45] | 36±16 [27 – 46] | 1.000 |
|
| |||
| QCT-vBMD L1 [mg/ml] | 135.85±34.84 [114.80 – 156.91] | 138.59±32.08 [119.21 – 157.98] | 0.762 |
| QCT-vBMD L2 [mg/ml] | 130.19±33.36 [110.04 – 150.35] | 138.05±32.21 [118.59 – 157.52] | 0.448 |
| QCT-vBMD L3 [mg/ml] | 122.34±32.12 [102.93 – 141.75] | 130.18±33.48 [109.95 – 150.41] | 0.336 |
| mean (L1–L3) QCT-vBMD [mg/ml] | 129.46±33.03 [109.50 – 149.42] | 135.60±32.21 [116.14 – 155.06] | 0.479 |
|
| |||
| bone marrow fat content L1 [%] | 65.9±7.8 [61.2 – 70.7] | 67.4±8.5 [62.0 – 72.9] | 0.418 |
| bone marrow fat content L2 [%] | 68.1±5.7 [64.6 – 71.5] | 68.9±7.1 [64.5 – 73.4] | 0.650 |
| bone marrow fat content L3 [%] | 68.4±5.9 [64.8 – 72.0] | 71.4±7.7 [66.5 – 76.4] | 0.223 |
| mean (L1–L3) bone marrow fat content [%] | 67.5±6.1 [63.8 – 71.2] | 69.3±7.5 [64.5 – 74.1] | 0.311 |
|
| |||
| bone marrow unsaturated lipid fraction L1 [%] | 7.5±2.2 [6.2 – 8.9] | 6.5±1.9 [5.3 – 7.7] | 0.101 |
| bone marrow unsaturated lipid fraction L2 [%] | 7.9±3.1 [6.1 – 9.8] | 6.6±2.6 [5.0 – 8.2] | 0.225 |
| bone marrow unsaturated lipid fraction L3 [%] | 8.2±2.3 [6.7 – 9.6] | 6.9±1.1 [6.3 –7.6] | 0.064 |
| mean (L1–L3) bone marrow unsaturated lipid fraction [%] | 7.9±1.6 [6.9 – 8.8] | 6.7±1.0 [6.0 – 7.3] | 0.006 |
|
| |||
| inner contour volume [cm3] | 3997±911 [3447 – 4548] | 4352±727 [3890 – 4814] | 0.437 |
| outer contour volume [cm3] | 6088±1976 [4894 – 7282] | 6401±1137 [5678 – 7123] | 0.538 |
| SAT [cm3] | 2090±1201 [1365 – 2816] | 2048±581 [1680 – 2417] | 0.650 |
| VAT [cm3] | 875±772 [408 – 1342] | 1153±401 [898 – 1408] | 0.137 |
| TAT [cm3] | 2965±1941 [1792 – 4138] | 3202±875 [2646 – 3757] | 0.406 |
| VAT/TAT [%] | 25.6±8.7 [20.4 – 30.9] | 35.8±6.7 [31.5 – 40.0] | 0.010 |
| SAT/inner contour volume [%] | 49.9±20.8 [37.3 – 62.4] | 47.1±11.6 [39.7 – 54.5] | 0.894 |
| VAT/inner contour volume [%] | 19.6±14.7 [10.8 – 28.5] | 25.9±6.1 [22.0 – 29.7] | 0.270 |
| TAT/outer contour volume [%] | 44.4±16.4 [34.5 – 54.2] | 49.2±6.5 [45.1 – 53.4] | 0.347 |