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. 2011 Nov 17;54(2):253–256. doi: 10.1093/cid/cir791

Table 1.

Prevalence of Clinically Active Trachoma and Ocular Chlamydial Infection Before Mass Treatments (Month 0), and 1 Year After 3 Annual Mass Azithromycin Treatments (Month 36)

Before Treatment
Treatment After 3 Mass Treatments
% (No./Total)
Mean (SD) % (No./Total)
Community TF/TIa DNAb % Coveragec TF/TIa DNAb RNAd
1 89.6 (43/48) 44.9 (22/49) 83.4 (9.2) 46.9 (23/49) 18.4 (9/49) 28.6 (14/49)
2 64.0 (32/50) 46.0 (23/50) 73.5 (12.3) 65.3 (32/49) 8.2 (4/49) 10.2 (5/49)
3 59.2 (29/49) 53.1 (26/49) 90.4 (5.2) 50.9 (27/53) 0.0 (0/53) 0.0 (0/53)
4 72.0 (36/50) 52.0 (26/50) 97.8 (2.3) 41.7 (20/48) 0.0 (0/48) 0.0 (0/48)
5 84.0 (42/50) 56.0 (28/50) 92.0 (5.3) 29.4 (15/50) 2.0 (1/50) 4.0 (2/50)
6 40.8 (20/49) 14.0 (7/50) 91.7 (6.6) 38.0 (19/50) 2.0 (1/49) 2.0 (1/49)
7 94.4 (34/36) 16.7 (6/36) 85.6 (3.0) 48.5 (16/33) 0.0 (0/33) 3.0 (1/33)
8 42.0 (21/50) 36.0 (18/50) 94.8 (3.7) 45.8 (22/48) 2.1 (1/48) 4.2 (2/48)
9 92.0 (46/50) 58.0 (29/50) 86.1 (5.0) 63.5 (33/52) 13.5 (7/52) 26.9 (14/52)
10 62.5 (30/48) 22.4 (11/49) 78.4 (30.0) 18.0 (9/50) 0.0 (0/51) 0.0 (0/51)
11 80.0 (40/50) 62.0 (31/50) 85.6 (4.4) 32.6 (14/43) 0.0 (0/45) 0.0 (0/45)
12 44.4 (20/45) 41.2 (21/51) 82.1 (11.5) 40.7 (22/54) 3.7 (2/54) 3.7 (2/54)
Mean (95% CI) 68.7 (56.3–81.2) 41.9 (31.5–52.2) 86.8 (82.4–91.2) 43.5 (35.0–52.0) 4.2 (0.3–8.0) 6.9 (0.4–13.3)

Abbreviations: CI, confidence interval; TF, follicular trachomatous inflammation; TI, intense trachomatous inflammation.

a

TF and/or TI, according to the World Health Organization simplified grading system [9].

b

DNA evidence of ocular chlamydia, tested with AMPLICOR-CT.

c

Mean antibiotic coverage during mass azithromycin distributions at months 0, 12, and 24.

d

RNA evidence of ocular chlamydia, tested with APTIMA-CT.