Figure 2. Impact of MSC Therapy assessed by MDCT.
(A–D) All placebo animals (n=8) showed an increase in infarct size (A) and infarct volume (C) at week 24, while intra-myocardial delivery of MSCs reduced infarct size (B) and stabilized infarct volume (D) in all treated animals (n=11).(E, F) LVEF is decreased at week 24 in placebo animals, while it increases in most MSC treated animals; however, in 2 animals the treatment failed to improve LVEF.