TABLE I.
Summarized literature review of pyramidal neuron models for CA1 and CA3 subfields in the hippocampus.
| Authors | CA | Number of compartments | Ionic currents | ||||
|---|---|---|---|---|---|---|---|
| Dendrites | Soma | Axon | Dendrites | Soma | Axon | ||
| Traub et al., 1991 [12] | 3 | 19 | INa, IKDR, IKC, IKA, ICa, IKAHP | ||||
| Pinsky et Rinzel, 1994 [8] | 3 | 1 | 1 | 0 | INa, IKDR | ICa, IKAHP, IKC, | |
| Warman et al., 1994 [15] | 1 | 16 | INa, ICa, IKDR, ICT, IA, IM, IAHP | ||||
| Migliore, 1996 [16] | 1 | 14 | 1 | 1 | If, INa, IKDR, Ih | If, INa, IKDR, Ih | INa, IKDR, IKM, Ih |
| Almeida et al., 1998 [17] | 1 | 6 | INa, IK | ||||
| Kamondi et al., 1998 [18] | 1 | 1 | 1 | 0 | INa, IK | INaP, IKS | |
| Migliore et al, 1999 [19] | 1 | 202 | INa, IKDR, IKA | INa, IKDR, IKA | INa, IKDR, IKA | ||
| Varona et al., 2000 [20] | 1 | 265 | INa, ICa, IKDR, IM, IA, IKC, IKAHP | ||||
| Menschik and Finkel., 2000 [21] | 3 | 385 | INa, IKDR, IKC, IKA, ICaT, ICaN, ICaL, IKAHP, Im | ||||
| Tiesinga et al., 2001 [22] | 3 | 1 | 1 | 0 | INa, IKDR | ICa, IKC, IKAHP, IM, IKO, INaO | |
| Sargsyan et al, 2001 [23] | 1 | 18 | 1 | 0 | INa, IKDR | ||
| Poolos et al., 2002 [24] | 1 | 202 | INa, IKDR, IKA,, Ih | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | ||
| Watanabe et al., 2002 [25] | 1 | 202 | INa, IKDR, IKA | INa, IKDR, IKA | INa, IKDR, IKA | ||
| Migliore, 2003 | 1 | 202 | INa, IKDR, IKA,, Ih | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | ||
| Poirazi et al, 2003 [26] | 1 | 183 | INa, IKDR, IKA, Ih, ICaT, ICaRR, ICaL, IAHP(SK), IAHP(BK), Im | INa, IKDR, IKA, Ih, ICaT, ICaRR, ICaL, IAHP(SK), IAHP(BK), Im | INa, IKDR, IKA, Ih, ICaT, ICaRR, ICaL, IAHP(SK), IAHP(BK), Im | ||
| Heilman and Quattrochi, 2004 [27] | 1 | 1 | 1 | 1 | INaT, IKDR, IKA,, IKCa, ICaL, ICaT, ICaR, ICaN | INaT, IKDR, IKA,, IKCa, ICaL, ICaT, ICaR, ICaN | INaT, IKDR, ICaN |
| Gasparini and al., 2004 [28] | 1 | INa, IKDR, IKA,, Ih | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | |||
| Hajòs et al, 2004 [29] | 1 | 256 | 0 | INa, IKDR, IKM, IKA, ICa, IKAHP, IKCT, Ih | |||
| Migliore et al., 2005 [14] | 1 | 202 | INa, IKDR, IKA,, Ih | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | ||
| Kali et Freund, 2005 [30] | 1 | 455 | 0 | INa, IKDRR, IKA, IKM, IKC, IKAHP, ICaT, ICaL, ICaN, ICaR, Ih | INa, IKDR, IKA, IKM, IKC, IKAHP, ICaT, ICaN | ||
| Golomb et al, 2006 [13] | 1 | 0 | 1 | 0 | INa, INaP, IKDR, IA,, IM | ||
| Golomb et al, 2006 [13] | 1 | 0 | 1 | 0 | INa, INaP, IKDR, IA, IM, ICa, IC, IsAHP | ||
| Li et Ascoli, 2006 [31] | 1 | 202 | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | INa, IKDR, IKA, Ih | ||
| Orbán et al, 2006 [32] | 1 | 256 | 0 | INa, IK, IKA, IKM, IKC, ICa, IKAHP, Ih | INa, IK, IKA, IKM, IKC, ICa, IKAHP | ||
| The present model | 1 | 1 | 1 | 0 | INa, IKA, IAHP(BK), IAHP(SK), IKDR, Ih,, Im, ICaR, ICaT | INa, IKDR, IAHP(BK), IAHP(SK), Im, ICaL | |