Table 2.
Altered Dopamine Receptor Signaling in NAcc
| Early Life vs No-GRov | Lifetime vs No-GRov | ||||
|---|---|---|---|---|---|
| Gene | RefSeq ID | FC | p | FC | p |
| ADCY1 | NM_009622 | 1.21 | .067 | −1.15 | .039 |
| ADCY7 | NM_001037724 | 1.14 | .031 | NC | |
| MAOA | NM_173740 | 1.14 | .029 | NC | |
| PPP1CA* | NM_031868 | −1.53 | .003 | NC | |
| PPP1R1B | NM_144828 | −1.37 | .001 | −1.21 | .012 |
| PPP2R5C* | NM_001081458 | −1.45 | .119 | NC | |
| PPP2R5D | NM_009358 | −1.17 | .024 | NC | |
| PRKAG1* | NM_016781 | −1.22 | .024 | NC | |
| AADC* | NM_016672 | NC | 1.75 | .029 | |
| IL4I1 | NM_010215 | NC | −1.17 | .012 | |
| PPP1CB* | NM_172707 | NC | 1.12 | .122 | |
| PPP1R12A* | NM_027892 | NC | 1.23 | .002 | |
| PPP1R14C* | NM_133485 | NC | 1.21 | .022 | |
| PPP1R3C* | NM_016854 | NC | 1.11 | .010 | |
| PPP2R5A | NM_144880 | NC | −1.10 | .017 | |
| SMOX | NM_001177836 | NC | 1.10 | .019 | |
Fold changes (FC) of gene expression represent either Lifetime or Early Life GRov mice compared with No-GRov controls. GRov, glucocorticoid receptor overexpression in forebrain; NAcc, nucleus accumbens; NC, no change. Genes with asterisk mark have been confirmed by qRT-PCR. n = 6–7 mice per group.