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. Author manuscript; available in PMC: 2012 Jun 22.
Published in final edited form as: Nature. 2011 Dec 14;480(7378):552–556. doi: 10.1038/nature10700

Figure 4.

Figure 4

Genetic loss of cryptochromes alters physiology. (a) Serum corticosterone. #P < 0.05 vs. ZT3-4. *P < 0.05, **P < 0.01 vs. wildtype. (b) Fasted and refed blood glucose **P < 0.01 vs. wildtype. (c) Glucose tolerance test. * P < 0.05, ** P < 0.01, ***P < 0.001 vs. wildtype. (d) Insulin tolerance test. (e) Corticosterone in sera collected at ZT10–11. (f) Fasted blood glucose. **P < 0.01 vs. saline-treated animals. ##P < 0.01 vs. wildtype. (g) Glucose tolerance tests. **P < 0.01 vs. saline-treated animals. In (a–d, f–g) data represent the mean ± s.e.m. for 6–8 animals per group.