Table 4.
Variables of contraction and Ca transients in diabetic and non-diabetic patients
| Variable | Spontaneous contractions | High K contraction | ||||
|---|---|---|---|---|---|---|
| Contractions | Ca signals | |||||
| Non-diabetic (n = 68) | Diabetic (n = 40) | Non-diabetic (n = 15) | Diabetic (n = 9) | Non-diabetic (n = 14) | Diabetic (n = 14) | |
| Frequency (contraction/h) | 8 (6, 12) | 7 (5, 13) | – | – | – | – |
| Amplitude (mN) | 2.4 (1.2, 4.5) | 1.5 (0.9, 2.6)* | 0.7 (0.3, 1.0) | 0.2 (0.1, 0.5) | 3 (1.3, 4.5) | 1.5 (0.8, 3.0)* |
| Duration (min) | 1.7 (1.1, 2.5) | 0.9 (0.6, 1.3)* | 2.0 (1.2, 3.3) | 1.0 (0.8,1.7)* | 2.1 (1.3, 3.6) | 1.2 (0.8, 1.8)* |
| AUC (au) | 8.7 (4.0, 14.5) | 2.1 (1.1, 3.5)* | 4.4 (2.0, 7.2) | 1.1 (0.6, 1.7)* | 5.4 (3.5, 16.4) | 2.8 (1.3, 3.5)* |
| Relaxation rate (min) | N/A | N/A | 5.0 (4.7, 9.1) | 2.4 (0.7, 4.5)* | N/A | N/A |
Median data with first and third quartiles in parenthesis
AUC for spontaneous contractions obtained over the last 20 min of the control period, whereas for KCl it was obtained from one contraction developed in response to 2 min exposure to high KCl
*p < 0.05
N/A, not available