Table 1.
Characteristics of participants by sex-specific quartiles of spKt/V
| Total (n = 273) | Kt/V, Q1 (n = 68) | Kt/V, Q2 (n = 68) | Kt/V, Q3 (n = 68) | Kt/V, Q4 (n = 69) | Trend p value | |
|---|---|---|---|---|---|---|
| Age, years | 63 ± 17 | 60 ± 17 | 63 ± 16 | 67 ± 15 | 64 ± 18 | 0.099 |
| Female | 47 | 47 | 47 | 48 | 47 | 0.932 |
| African American | 22 | 24 | 31 | 16 | 16 | 0.092 |
| Education | 0.045 | |||||
| <12th grade | 10 | 16 | 4 | 4 | 13 | |
| High school graduate | 58 | 49 | 69 | 56 | 59 | |
| 2+ years college | 32 | 35 | 26 | 40 | 28 | |
| Medical history | ||||||
| Peripheral vascular disease | 22 | 25 | 15 | 29 | 19 | 0.862 |
| Coronary artery disease | 33 | 28 | 29 | 41 | 35 | 0.207 |
| Hypertension | 87 | 82 | 90 | 88 | 88 | 0.357 |
| Stroke | 20 | 22 | 18 | 21 | 19 | 0.755 |
| Diabetes | 48 | 56 | 54 | 46 | 35 | 0.008 |
| Heart failure | 34 | 34 | 37 | 35 | 30 | 0.647 |
| Primary cause of ESRD | 0.042 | |||||
| Diabetes | 37 | 44 | 45 | 40 | 19 | |
| Glomerulonephritis | 18 | 21 | 11 | 12 | 28 | |
| Hypertension | 20 | 12 | 20 | 21 | 26 | |
| Other | 19 | 16 | 17 | 19 | 23 | |
| Unknown | 7 | 7 | 8 | 9 | 4 | |
| Smoking history | 0.034 | |||||
| Never | 38 | 40 | 39 | 32 | 40 | |
| Past | 55 | 52 | 46 | 68 | 52 | |
| Current | 8 | 8 | 15 | 0 | 8 | |
| spKt/V | 1.51 ± 0.24 | 1.25 ± 0.10 | 1.42 ± 0.09 | 1.56 ± 0.09 | 1.79 ± 0.19 | <0.001 |
| Systolic BP, mm Hg | 143 ± 21 | 142 ± 22 | 146 ± 20 | 141 ± 20 | 142 ± 21 | 0.713 |
| Diastolic BP, mm Hg | 73 ± 12 | 75 ± 14 | 74 ± 2 | 71 ± 11 | 73 ± 12 | 0.163 |
| BMI (kg/m2) | 28 ± 7 | 31 ± 9 | 29 ± 6 | 27 ± 6 | 26 ± 6 | <0.001 |
| Hematocrit, % | 36 ± 3 | 36 ± 4 | 36 ± 3 | 35 ± 3 | 35 ± 3 | 0.020 |
| Serum albumin, g/dl | 3.8 ± 0.3 | 3.8 ± 0.4 | 3.9 ± 0.3 | 3.9 ± 0.4 | 3.9 ± 0.3 | 0.061 |
| Phosphate, mg/dl | 5.5 ± 1.5 | 5.8 ± 1.9 | 5.3 ± 1.5 | 5.1 ± 1.2 | 5.5 ± 1.4 | 0.463 |
| Dialysis vintage, months | 13 (6-32) | 9 (4-19) | 12 (5-28) | 17 (10-38) | 19 (11-39) | <0.001 |
| PTH, pg/ml | 223 (143-390) | 226 (129-414) | 227 (141-332) | 217 (152-343) | 225 (145-403) | 0.996 |
Continuous data shown are means ± SD, except dialysis vintage and PTH which are medians (interquartile range); categorical data are presented as percentages. p values for education, primary cause of ESRD and smoking are from a χ2 test. p values for dialysis vintage and PTH are from the Kruskal-Wallis test. Conversion factors for units: albumin in g/dl to g/l, multiply by 10; phosphate in mg/dl to mmol/l, multiply by 0.3229. BP = Blood pressure; PTH = parathyroid hormone.