. Author manuscript; available in PMC: 2012 Oct 1.

Published in final edited form as: Lancet Oncol. 2011 Oct 6;12(13):1214–1221. doi: 10.1016/S1470-2045(11)70260-1

Table 1.

Donor-recipient HLA-match categories

Variable	Number (%)
Total number	803
Donor-recipient HLA-match I
HLA-A, -B, -C, -DRB1 match	69 (9%)
1-locus HLA-A, -B, -C, -DRB1 mismatch	147 (18%)
2-loci HLA-A, -B, -C, -DRB1 mismatch	259 (32%)
3-loci HLA-A, -B, -C, -DRB1 mismatch	253 (32%)
4-loci HLA-A, -B, -C, -DRB1 mismatch	75 (9%)
Donor-recipient HLA-match II
HLA-A, -B -DRB1 match + C match	69 (9%)
HLA-A, -B -DRB1 match + C mismatch^*	23 (3%)
1-locus HLA-A, -B -DRB1 mismatch + C match	127 (16%)
1-locus HLA-A, -B -DRB1 mismatch + C mismatch^†	234 (29%)
2-loci HLA-A, -B -DRB1 mismatch + C match	57 (7%)
2-loci HLA-A, -B -DRB1 mismatch + C mismatch^‡	293 (36%)
Donor-recipient HLA-match III
HLA-A, -B -C match + DRB1 match	69 (9%)
HLA-A, -B -C match + DRB1 mismatch^**	51 (6%)
1-locus HLA-A, -B, -C mismatch + DRB1 match	101 (12%)
1-locus HLA-A, -B, -C mismatch + DRB1 mismatch^††	77 (10%)
2-loci HLA-A, -B, -C mismatch + DRB1 match	181 (23%)
2-loci HLA-A, -B, -C mismatch + DRB1 mismatch^‡‡	119 (15%)
≥3-loci HLA-A, -B, -C mismatch + DRB1 match/mismatch^§	205 (26%)
Donor-recipient HLA-match IV
HLA-B, -C –DRB1 match + A match	69 (9%)
HLA-B, -C –DRB1 match + A mismatch	62 (8%)
1-locus HLA-B, -C –DRB1 mismatch + A match	88 (11%)
1-locus HLA-B, -C –DRB1 mismatch + A mismatch	78 (10%)
2-loci HLA-B, -C –DRB1 mismatch + A match	181 (22%)
2-loci HLA-B, -C –DRB1 mismatch + A mismatch	140 (17%)
≥3-loci HLA-B, -C –DRB1 mismatch + A match/mismatch^§§	185 (23%)
Donor-recipient HLA-match V
HLA-A, -C –DRB1 match + B match	69 (9%)
HLA-A, -C –DRB1 match + B mismatch	24 (3%)
1-locus HLA-A, -C –DRB1 mismatch + B match	125 (16%)
1-locus HLA-A, -C –DRB1 mismatch + B mismatch	153 (19%)
2-loci HLA-A, -C –DRB1 mismatch + B match	112 (14%)
2-loci HLA-A, -C –DRB1 mismatch + B mismatch	193 (24%)
≥3-loci HLA-A, -C –DRB1 mismatch + B match/mismatch^§§§	127 (16%)

3 of 23 donor-recipient pairs mismatched at HLA-C were mismatched at both loci

^†

35 of 234 donor-recipient pairs mismatched at HLA-C were mismatched at both loci

^‡

75 of 293 donor-recipient pairs mismatched at HLA-C were mismatched at both loci

^**

5 of 51 donor-recipient pairs mismatched at HLA-DRB1 were mismatched at both loci

^††

4 of 77 donor-recipient pairs mismatched at HLA-DRB1 were mismatched at both loci

^‡‡

2 of 119 donor-recipient pairs mismatched at HLA-DRB1 were mismatched at both loci

^§

168 donor-recipient pairs were matched at HLA-DRB1 and 37 were mismatched at a single DRB1 locus

^§§

151 donor-recipient pairs were matched at HLA-A and 34 were mismatched at a single A locus

^§§§

70 donor-recipient pairs were matched at HLA-B and 57 were mismatched at a single B locus