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. Author manuscript; available in PMC: 2012 May 23.
Published in final edited form as: Immunity. 2011 Nov 10;35(5):757–769. doi: 10.1016/j.immuni.2011.09.011

Figure 5. CD45 and CD148 differentially regulate signaling events following fMLF stimulation.

Figure 5

(A) BM cells from mice of the indicated genotypes were stimulated with fMLF (0.2 μM) for indicated time, fixed, permeabilized, and then stained with phospho-Akt along with other surface makers. Neutrophils were identified as CD11b+Gr1+. Phospho-Akt of stimulated (2.5 min, shown as black lines) and control samples (shown as filled histograms) were overlaid. Percentages of pAkt+ cells over a time course are shown on the right side. Data are representative of three independent experiments. (B) BM cells were treated same as in (A) and phospho-ERK was stained similarly. Percentages of pERK+ cells over a time course are shown on the right side. Data are representative of three independent experiments.