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. 2011 Sep 10;40(1):116–131. doi: 10.1093/nar/gkr685

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Promoter methylation and expression of ten key genes of the hematopoietic system. For each gene, we depict (from top to bottom): the diagram showing the genomic region surrounding the transcriptional start site (TSS, arrow). Thin black vertical bars indicate CpG position and a grey horizontal bar indicates the location (distance in base pair from TSS) of the probe used in methylation arrays and validated by pyrosequencing in the indicated samples; percentage of promoter methylation as detected in the pyrosequencing reaction; percentage of promoter methylation as detected in the Illumina Infinium array and mRNA expression relative to GAPDH as measured by qRT–PCR in the indicated samples (n = 3, mean ± SD).