Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular models of 3′-azido-ddGTP (A), 3′-azido-6-Cl-P-TP (B), 3′-azido-ddATP (C) and 3′-azido-2,6-DA-P-TP (D) in the DNA polymerase active site of HIV-1 RT. Each of the analogs was modeled into the ternary RT-T/P-TTP complex (pdb co-ordinates 1RTD). A schematic representation of the hydrogen-bonding patterns between the incoming nucleotide analog and the template base is depicted below each model.
