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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Anesthesiology. 2011 Dec;115(6):1192–1200. doi: 10.1097/ALN.0b013e318238f445

Figure 3.

Figure 3

Panel A illustrates the differential effect of 24.5 μM Rp-adenosine-3′,5′-cyclic monophosphorothioate (cAMPs) and 2.5 μM (Rp)-8-(para--chlorophenylthio)guanosine-3′,5′-cyclic monophosphorothioate (cGMPs) on the hyperpolarization response to 5.0 μM 2,6-diisopropylphenol. cAMPs abolished the response in both the Dahl Salt Sensitive rat strain (SS/JrHsdMcwi, abbreviated as SS) and the Brown Norway rat strain (BN/NhsdMcwi abbreviated as BN) , whereas cGMPs abolished the response in BN but not in SS. cGMPs also abolished the response in Line 3 but not in Line 2 of SS.13BN consomic rat strain. Bars represent mean ± standard deviation. Panel B is a scatter plot of all individual data points comprising the means illustrated in panel A. * = p ≤ 0.05 vs respective control, † = p ≤ 0.05 vs BN, n = 3 - 6 animals.