Table 4.
Statistical study of the 4 major groups identified by FCI. %: median percentage of CSF cells. Interquartile range is specified inside brackets
| CSF data | TP (n = 32) | TN (n = 25) | FN (n = 12) | TP FCI (n = 5) |
|---|---|---|---|---|
| Volume | 2.7 (2.1–3.5) | 2.6 (2.1–3.3) | 2.4 (1.4–3.2) | 2.3 (2.1–2.7) |
| Cells/mm3 | 8.0 (4.8–40.8)a | 1.0 (<1–7.0) | 1.0 (<1–4.7) | <1 |
| % epithelial cells | 14 (3.0–26.5)b | 0 | 0 | 3.0 (1.5–8.5)c |
| Epithelial cells/mm3 | <1 (<1–3.75)b | <1 | <1 | <1 (<1–3.0) |
| % lymphocytes | 55 (40–73)d | 73 (41–87)e | 49 (19–62) | 40 (30–65) |
| % monocytes | 35 (19–49) | 17 (9–31)f | 39 (18–57) | 48 (28–68) |
| % PMN | 4 (1–13) | 0 (0–15) | 2 (0–23) | 6 (0–13) |
Abbreviations: TP, true positive for malignancy cytology concordant; TN, true negative for malignancy cytology concordant; FN, false negative cytology/FCI; TP FCI, false negative cytology/true positive FCI; PMN, polimorphonuclear; FCI, flow cytometry immunophenotyping.
aP < .01 vs TN, FN and TP FCI groups.
bP < .001 vs TN and FN groups.
cP≤ .001 vs TN and FN groups.
dP < .05 vs TN group.
eP < .01 vs FN group.
fP < .01 vs TP, FN, and TP FCI groups.