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. Author manuscript; available in PMC: 2013 Jan 11.
Published in final edited form as: Vaccine. 2011 Nov 29;30(3):506–509. doi: 10.1016/j.vaccine.2011.11.079

Fig. 1.

Fig. 1

Selection of HIV-1 Gag antigens for heterologous insert prime-boost immunization. (A) Individual clade C sequences were compared against the M consesnsus sequence to determine the circulating frequency of shared PTEs among clade C isolates or in the M group as a whole. Isolates with a high circulating frequency by both criteria were evaluated for the total number of shared PTEs with GagConM in order to maximize the sensitivity for detecting selective boosting of conserved epitopes. (B) The mean circulating frequency of PTEs shared between GagConM and GagCZA was compared with the mean circulating frequency of divergent PTE among clade C isolates or in the M group as a whole.