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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2012 Jan;71(1):73–82. doi: 10.1097/NEN.0b013e318240fa65

Figure 2.

Figure 2

10q loss of heterozygosity (LOH) in gliomas. (A) 23.6% of grade II oligodendrogliomas had 10q LOH vs. 34.6% of grade III oligodendrogliomas (p = 0.40 by Mann-Whitney test). (B) When either a grade II or grade III oligodendroglioma was called 1p/19q-codeleted by fluorescence in situ hybridization (FISH), concordance with PCR-based 1p/19q microsatellite LOH analysis was much less likely if 10q was also deleted (p < 0.0001, n = 76). (C) If an oligodendroglioma was 1p/19q-intact by FISH, 10q status had no bearing on whether the FISH result would be concordant with PCR-based 1p/19q microsatellite analysis (p = 0.41, n = 22).