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(A) Human VEGF immunohistochemistry in a calvarial defect (brown color) with control shRNA or Noggin shRNA hASCs on a HA coated PLGA scaffold with or without BMP-2 (200ng/ml). (B) VEGFA expression by immunofluorsence (red color) in the region of the calvarial defect treated either with control shRNA treated or Noggin shRNA treated hASCs.
