Table 7.
Dose-Time Point | [Clop] (ng/mL) Without MPB (Mean ± SE; n=18) |
Mean [Clop] (ng/mL) With MPB (Mean ± SE; n=18) |
P-value |
---|---|---|---|
75mg-0.25 hr | 0.3161 ± 0.0897 | 0.3144 ± 0.0849 | 0.9291 |
75mg-0.50 hr | 1.065 ± 0.3115 | 1.017 ± 0.3035 | 0.2287 |
75mg-1.0 hr | 1.189 ± 0.5259 | 1.123 ± 0.4693 | 0.3310 |
75mg-2.0 hr | 0.3381 ± 0.1110 | 0.3505 ± 0.1100 | 0.5405 |
75mg-4.0 hr | 0.0348 ± 0.0071 | 0.0315 ± 0.0069 | 0.1818 |
150mg-0.25 hr | 0.4487 ± 0.1687 | 0.4956 ± 0.1770 | 0.0554 |
150mg-0.50 hr | 1.612 ± 0.5310 | 1.569 ± 0.4856 | 0.5259 |
150mg-1.0 hr | 1.839 ± 0.5590 | 1.923 ± 0.5674 | 0.5867 |
150mg-2.0 hr | 1.097 ± 0.2681 | 1.059 ± 0.2583 | 0.0930 |
150mg-4.0 hr | 0.1663 ± 0.0467 | 0.1435 ± 0.0370 | 0.0914 |
300mg-0.25 hr | 0.6800 ± 0.3236 | 0.6556 ± 0.2937 | 0.4857 |
300mg-0.50 hr | 2.151 ± 0.7728 | 2.172 ± 0.8208 | 0.7937 |
300mg-1.0 hr | 3.191 ± 1.152 | 3.217 ± 1.200 | 0.6755 |
300mg-2.0 hr | 1.816 ± 0.6160 | 1.674 ± 0.5467 | 0.1053 |
300mg-4.0 hr | 0.3586 ± 0.1068 | 0.3381 ± 0.1000 | 0.1002 |