Table 1.

Average concentrations of ospemifene and 4-OH ospemifene in the tumors and plasma of mice in each cohort of the prevention and treatment experiments.

a.
Prevention	4-OH OSP		OSP		n
Group	Plasma (nM)	Tumor (nmol/g)	Plasma (nM)	Tumor (nmol/g)
Osp 5 mg/kg	96.5	0.05	72.6	0.07	7
Osp 25 mg/kg	760.2	0.35	446.3	1.71	8
Osp 50 mg/kg	2505.2	0.92	2013.2	4.04	8
Control animals (n=10) had no detectible peaks

b.
Treatment	4-OH OSP		OSP		n
Group	Plasma (nM)	Tumor (nmol/g)	Plasma (nM)	Tumor (nmol/g)
Osp 5 mg/kg	53.2	0.05	42.2	0.07	5
Osp 25 mg/kg	397.1	0.26	181.8	0.66	2
Osp 50 mg/kg	1015.4	0.99	1947.2	3.43	3
Control animals (n=10) had no detectible peaks