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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Kidney Int. 2011 May 4;80(7):719–730. doi: 10.1038/ki.2011.122

Table 2.

Characterization of renal disease in NPHS2-Cre; Droshafl/fl and NPHS2-Cre; Dicerfl/fl mice

NPHS2-Cre; Drosha+/+ NPHS2-Cre; Droshafl/fl NPHS2-Cre; Dicerfl/fl
Proteinuria − +++ +++
Glomerular sclerosis & collapse* 0% 71.9% 73.4%
Tubular microcysts* 0 3+ 3+
Podocyte phenotype** Normal Abnormal Abnormal
Foot process effacement 0% 100% 100%
Primary Processes Present Absent Absent

Note:

*

See Table 1 legend for details;

**

details of podocyte phenotype in regard to podocin, nephrin, synaptopodin, WT-1, Ki-67, SMA, desmin, nestin are discussed in the text and shown in Table 2.