Table 4. Summary of Affinity Training Sets^a.

	Protein target	No. of complexes	pIC50 range
I	Neuraminidase	31	6.7–10.0
II	PDE10	46	5.7-10.0
III	IRAK4	10	5.1-8.3
	BTK	9	4.2-7.9
	HCV polymerase	9	3.9-7.6
	HIV protease	8	6.9-9.7
	DPP-IV	2	6.4-8.0
	PKACA	2	5.5-5.7
	LCK	2	7.7-9.3
IV	see Table 5

^aProtein target abbreviations are PDE10, phosphodiesterase 10; IRAK4, interleukin-1 receptor-associated kinase 4; BTK, Bruton’s tyrosine kinase; DPP-IV, dipeptidyl peptidase 4; PKACA, cAMP dependent protein kinase; LCK, lymphocyte-specific protein kinase.