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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: J Immunol. 2011 Oct 17;187(10):5336–5345. doi: 10.4049/jimmunol.1100040

Figure 8.

Figure 8

Effect of etoposide on murine embryo fibroblasts. Murine embryo fibroblasts (MEFs) isolated from wt mice, or mice with targeted gene knockouts in NEMO (NEMO−/−), IRF-3 (IRF3−/−), IRF-1 (IRF1−/−), or IRF-7 (IRF7−/−) were untreated or treated with etoposide for 24 hours. Real-time RT-PCR was used to quantify endogenous levels of murine IFNλ2 (top) or pan- IFNα (bottom). Quantitative results are means of duplicate determinations in three independent experiments.