Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reduction of KO to vitamin K by Mt-VKORH cysteine mutants to support carboxylation in HEK293 cells. Mt-VKORH and its cysteine mutants were transiently expressed in FIXgla-PC/HEK293 cells and the enzymatic activity was determined as described in the legend of Figure 1. The control is transfection of the expression vector into the above cell line. Data are presented as mean±SD (n=3). *p<0.001, compared with control.
