Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Dec 27;6(12):e29166. doi: 10.1371/journal.pone.0029166

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Kalis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Pancreatic islets were isolated from 7 RIP-Cre Dicer1^Δ/Δ and 7 littermate control mice. β-cells were sorted using flow cytometry to >98% purity. Total RNA was extracted and used for qPCR and array hybridization. A. Insulin mRNA expression level is reduced in RIP-Cre Dicer1^Δ/Δ, B. Mature miR-375 is significantly reduced while the pri-miR-375 species accumulates in the knockout. ***P<0.001.