Table 1. Systemic hemodynamics.
Mice | n | HR, beats/min | SAP, mmHg | DAP, mmHg | MAP, mmHg |
Control | 7 | 450±70 | 115±13 | 62±15 | 80±12 |
Hypoxia | 7 | 513±49 | 100±5.8* | 50±17 | 67±12* |
Hypoxia+Iso | 6 | 463±77 | 93±8.8* | 42±7.3 | 58±5.6* |
Hypoxia+Sev | 6 | 448±34 | 89±8.7* | 54±12 | 65±10* |
Six-week-old BALB/c mice were divided into 4 groups; control (exposed to air), hypoxia (exposed to 10% O2 for 3 hours), hypoxia+iso (exposed to 10% O2 with 0.5% isoflurane for 3 hours) and hypoxia+sev (exposed to 10% O2 with 0.5% sevoglurane for 3 hours). Immediately after the hypoxic exposure, heart rate and blood pressure were measured.
There were no significant differences in any of the parameters among hypoxia, hypoxia+iso and hypoxia+sev group mice. Values are shown as mean ± SD. * P<0.05 versus control.
HR = heart rate; SAP = systolic arterial pressure; DAP = diastolic arterial pressure; MAP = mean arterial pressur.