Table 3. Single marker association with cerebral malaria and uncomplicated malaria.
Marker | Alleles | Associated Allele | UM Freq. (n = 105) | CM Freq. (n = 45) | p - value | OR (95% CI) |
rs2233858 | C/T | T | 0.03 | 0.04 | 9.47×10−1 | 1.05 (0.26–4.30) |
rs2073342 | C/G | G | 0.27 | 0.45 | 9.45×10−3 | 2.29 (1.22–4.32) |
rs2233860 | G/C | G | 0.72 | 0.81 | 4.94×10−1 | 1.22 (0.68–2.21) |
rs8019343 | A/T | T | 0.14 | 0.16 | 1.37×10−1 | 0.53 (0.22–1.24) |
The frequency of the associated allele in uncomplicated malaria (UM) and CM is shown. Odds Ratios (OR) and 95% confidence intervals (CI) were determined using multivariate logistic regression controlling for age and gender. The reference groups in the multivariate logistic regression analyses were those without the respective alleles.