Figure 5. Immunoblot analyses of selected mitochondrial proteins in BAT from Tk2 H126N knockin mice.
A. Bars are means ± SEM of density of specific immunoblot signals normalized to total protein load (*P<0.05 for Tk2+/+ vs. Tk2-/-; 4-6 mice/group). B. Representative western blots. ATPsyn α (CV), ATP synthase subunit α (Complex V); Core 2 (CIII), Core 2 subunit (Complex II); COI (CIV), cytochrome c oxidase subunit 1 (Complex IV); Ip30 kD (CII), 30 kD subunit (Complex II); ND6 (CI), NADH dehydrogenase subunit 6 (Complex I); OPA1, Optic atrophy 1 protein; TFAM, mitochondrial transcription factor A; VDAC, voltage-dependent anion carrier; UCP1, uncoupling protein 1.
