Table 3. Haplotype frequencies for the GSTT1 and GSTT2B deletion polymorphisms in Black and Mixed Ancestry populations.
Population | Haplotype | Control Frequency | Linkage Disequilibrium | ||||
GSTT1 – GSTT2B | Obs | Exp | r2 | D′ | OR | p-value | |
Black | 0.04 | 0.27 | |||||
Wt – Wt | 0.2268 | 20.21 | 1 (reference) | - | |||
DEL – Wt | 0.4004 | d0.35 | 1.000 (0.74–1.36) | 1.0000 | |||
Wt – DEL | 0.2223 | e0.165 | 0.814 (0.56–1.18) | 0.2796 | |||
DEL – DEL | 0.1505 | 30.28 | 0.912 (0.65–1.29) | 0.6006 | |||
Mixed Ancestry | 0.07 | 0.33 | |||||
Wt – Wt | 0.1711 | 0.25 | 1 (reference) | - | |||
DEL – Wt | 0.3313 | 0.25 | 0.766 (0.52–1.12) | 0.1705 | |||
Wt – DEL | 0.3337 | 0.25 | 0.584 (0.39–0.87) | 0.0078 | |||
DEL – DEL | 0.1639 | 0.25 | 0.583 (0.39–0.88) | 0.0083 |
p-value is for comparing each haplotype to the reference Wt-Wt haplotype.