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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Stroke. 2011 Nov 10;43(1):178–184. doi: 10.1161/STROKEAHA.111.632265

Table 1.

Ultra-structural analysis of axons in chronic WMI found no axonopathy in major lesions with diffuse astrogliosis at 1 or 2 weeks after H-I.

Region Axon Density (axons/100μm2) Degenerating Axon Density (axons/100μm2) Mean Axon Diameter (nm) N (axons)
SWM
 1 wk Control 332 ± 58 9 ± 2 188 ± 14 1163
H-I 323 ± 41 11 ± 2 203 ± 15 1256
 2 wk Control 344 ± 68 11 ± 2 181 ± 11 958
H-I 310 ± 65 12 ± 1 191 ± 10 968
DWM
 1 wk Control 273 ± 24 8 ± 3 206 ± 9 925
H-I 321 ± 17 11 ± 1 209 ± 13 1362
410 ± 33 †
 2 wk Control 14 ± 3 204 ± 6 1047
H-I 364 ± 47 15 ± 2 203 ± 9 993

Shown are the total density of axons, density of degenerating axons, mean axon diameter and total number of axons analyzed in each study (N). Data are presented as mean ± SEM, n = 4 animals per group.

†

p < 0.05 vs. 1 week control (ANOVA with post hoc Bonferroni between groups).