Table 3.
DMP1-SOST transgenic mice exhibit no changes in volume or geometry of ulna cortical bone or length of long bones
| bone | parameters | unit | female (16-week-old) | |
|---|---|---|---|---|
| WT | TG | |||
| ulna midshaft (cortical) |
T.Ar. | mm2 | 0.33 ± 0.02 | 0.31 ± 0.02 |
| B.Ar. | mm2 | 0.27 ± 0.01 | 0.277 ± 0.005 | |
| M.Ar. | mm2 | 0.05 ± 0.01 | 0.05 ± 0.02 | |
| Ct. Th. | mm | 0.16 ± 0.01 | 0.16 ± 0.01 | |
| Imin | ×10−2 mm4 | 0.44 ± 0.04 | 0.38 ± 0.06 | |
| Ma.D. | pixel | 203.72 ± 5.82 | 210.37 ± 2.16 | |
| n | 8 | 3 | ||
| bone | parameters | unit | female (16-week-old) | male (16-week-old) | ||
|---|---|---|---|---|---|---|
| WT | TG | WT | TG | |||
| femur | length | mm | 15.31 ± 0.50 | 15.14 ± 0.16 | 15.52 ± 0.33 | 15.10 ± 0.45 |
| tibia | length | mm | 17.74 ± 0.73 | 17.96 ± 0.29 | 18.08 ± 0.19 | 17.93 ± 0.29 |
| n | 6 | 5 | 5 | 5 | ||
T. Ar., tissue area; B.Ar., bone area; M.Ar., marrow area; Ct.Th., cortical thickness; Imin, minimum second moment of area; Ma.D., material density.
Values are means ± SD.