SEM micrographs of formulation 503H composites after exposure to PBS (pH 7.4): (A) 1 day, at 45°C; (B) 7 days, at 45°C; (C) 1 day, at 50°C; (D) 5 days, at 50°C; (E) 3 days, at 53°C; (F) 4 hours, at 60°C; Symbol: white arrow - “inside-out” degrading PLGA microspheres. Scale bar: 20 µm.