Table III.

Summary of In Vitro Release of Octreotide-Loaded PLHMGA Microspheres of Different Composition (n = 3) and PLGA Microspheres in PBS (pH 7.4) at 37°C

Batch	% of the loaded amount released	% burst release a	% native octreotidec	Microspheres degradation (days)	Duration of release
PLHMGA 75/25	69.6 ± 7.0	18.5 ± 0.5	74.5 ± 0.3	55	75
PLHMGA 65/35	82.1 ± 5.0	21.1 ± 0.2	65.6 ± 1.5	35	60
PLHMGA 50/50	84.5 ± 4.0	23.7 ± 0.3	68.3 ± 3.2	20	20
bPLGA	85	no	25	90	95

^aDefined as the amount released after 24 h

^bResults are from a single batch

^cDefined with respect to the total octreotide that was released