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. 2012 Jan;19(1):9–14. doi: 10.1101/lm.024042.111

Figure 1.

Figure 1.

Validation of the cued fear conditioning experimental paradigm. Cued fear conditioning of Sprague-Dawley rats, no cannulations. Paired animals froze more during the tone presentation than unpaired animals in a distinct context (F(1,9) = 8.39, paired n = 5, unpaired n = 5; * denotes significant difference between paired and unpaired animals, P < 0.02). Differences between pretone and tone freezing demonstrate that freezing is tone-dependent in the paired group only (F(1,4) = 34.10, P < 0.001; # denotes significant difference between pretone and tone-dependent freezing in the paired group; unpaired: F(1,4) = 1.10, P > 0.05). Error bars represent SEM.