Table 2.

Effects of rimonabant on serum biochemical parameters in HC-fed ApoE3 mice after 28 days treatment

Metabolic parameters	Vehicle	Rimonabant (20 mg·kg−1)
Body weight (g)	26.5 ± 0.81	23.9 ± 0.69*
LDL (mM)	2.4 ± 0.21	1.61 ± 0.11*
HDL (mM)	1.84 ± 0.06	1.95 ± 0.09
Triglyceride (mM)	2.62 ± 0.05	1.59 ± 0.07*
Total cholesterol (mM)	14.93 ± 0.58	10.09 ± 0.41*
FFA (mM)	1.89 ± 0.16	1.25 ± 0.10*
CRP (ng·mL−1)	62.3 ± 7.10	48.3 ± 3.61*
MCP-1 (pg·mL−1)	842.3 ± 42.1	645.8 ± 56.2*
Adiponectin (µg·mL−1)	23.2 ± 2.2	27.6 ± 2.8
RBP4 (µg·mL−1)	57.3 ± 3.2	48.1 ± 2.1*

Values are shown as mean ± SEM.

^*P < 0.05 as compared to vehicle control.