Figure 2.

Effects of a single s.c. administration of mephedrone (1 and 3 mg·kg⁻¹), MDMA (3 mg·kg⁻¹) and amphetamine (1 mg·kg⁻¹) on (A) extracellular levels of DA and (B) extracellular levels of 5-HT in the NAcc of awake rats. The arrow indicates the time of drug or vehicle administration. Repeated measures two-way anova followed by Bonferroni post-test; the drug-treated groups were compared with the vehicle group: mephedrone (1 mg·kg⁻¹) ^cccP < 0.001, ^cP < 0.05; mephedrone (3 mg·kg⁻¹) ^eeeP < 0.001, ^eeP < 0.01; MDMA ^dddP < 0.001, ^ddP < 0.01; amphetamine ^aaaP < 0.001, ^aP < 0.05; mean ± SEM, n = 4.